the protective fluid surrounding an embryo in mammals.
Glossary
Animal pole
the region where cells are mainly localized - the opposite pole is the vegetal pole, where the yolk is mainly localized.
Anterior-posterior axis
one of the body axis running from the head of the organism down to the lower limbs.
Arthropod
an invertebrate without an internal skeleton, instead the organism is protected by an external case - an exoskeleton.
Blastpore
a hole in the embryo which opens on to the primitive gut.
Blastula
the early embryo simply consisting of a ball of cells.
Cadherin
a cell adhesion molecule.
CAM
Cell adhesion molecules - molecules which allow cell-cell and cell-extra cellular matrix binding.
Differentiation
the specialization of a cell’s fate into a certain pathway - e.g. neural, muscle etc.
Dorsal
the dorsal or back of the organism. The dorsal-ventral axis is one of the body axis, others are the anterior (head) to posterior (feet) axis.
Glia
non neuronal cells present in the nervous system, which support neurons and play important roles in signaling.
Growth factor
a secreted signaling molecule that can induces growth in receptive cells.
Homolog
see homologous.
Homologous
two proteins in different species with very similar DNA sequences.
Medio-lateral
one of the body axis running from the midline of the body across to the outer side.
Mesenchyme
a cell type that can migrate through tissues and does not have regular tissue boundaries or cell-cell adhesion.
Midline
an imaginary line running down the middle of an organism.
Morphogen
a secreted signaling molecule which causes different effects on cells in a concentration-dependent way.
Neuroblast
a partially differentiated cell who will either differentiate into a neuron or glia cell.
Organizer
a group of cells which secrete morphogens and induce cell fate throughout the embryo.
Organogenesis
the process where, after Gastrulation, the three germ layers begin to create the major internal organs.
Pluripotent
a non-differentiated cell which can develop into any cell in the adult body.
Precursor
a cell, which hasn’t fully transitioned into it’s final state.
Proliferation
cell division and growth - vital in the embryo as a single cell creates an entire organism.
Somite
groups of mesodermal cell distributed along either side of the neural tube. They form vertebrae amongst other things.
Transcription factor
a DNA binding protein which increases transcription of certain genes.
Vegetal pole
the pole at which mostly yolk is localized. See dorsal pole.
Ventral
the front side of the embryo - see dorsal.
Yolk
nutrient-rich fluid attached to embryos who are not able to get nutrients from their mother via a sack. Found in amphibians, reptiles and birds.